In this two-part episode, Sam Matz (MS3) sits down with Dr. Kusin, of Oregon Health and Science University in the department of Toxicology and Emergency Medicine.

In part one, Dr. Kusin discusses a case report of two Oregon men who develop severe methemoglobinemia and hemolytic anemia from the consumption of aniline purchased as 2C-E, a recreational drug from the internet. Our two patients, lovingly referred to as “Brutus” and “The Poet” are followed through their hospital course, beginning with the ingestion of what they thought would be a novel elicit substance purchased from China. We hear of their start with Mountain Dew to increase palatability of their purchase, a late night in a Wendy’s parking lot, to FBI involvement for suspected product tampering, and later culminating in leaving against medical advice and subsequent return. An excellent story-teller, Dr. Kusin provides an excellent recount of this fascinating story and case report.

In Part two, we return to our visit with Dr. Kusin and discuss methemoglobinemia as a teaching topic, touch on clinical pearls surrounding treatment, and how to avoid common pitfalls in the recovery pathway. Later we talk of the path to Toxicology and Emergency medicine, general medical school advice, and few anecdotes to keep things spicy. I hope you enjoy this episode of EMIGcast.


Dr. Kusin is an assistant professor in the department of Emergency Medicine and fellow of Toxicology at Oregon Health and Science University in Portland, Oregon.

Sam Matz is a 3rd year medical student at Oregon Health and Science University and member of EMIG and EMIGcast.


Severe Methemoglobinemia and Hemolytic Anemia from Aniline Purchased as 2C-E (4-ethyl-2,5-dimethoxyphenethylamine), a Recreational Drug, on the Internet — Oregon, 2011


Disclaimer: The contents, including all opinions and views expressed, in this episode are entirely personal and do not necessarily represent the opinions or views of anyone else, including other faculty, students or staff at Oregon Health & Science University. Oregon Health & Science University have not approved and are not responsible for the material contained in this podcast.

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